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Pathogen blockade of TAK1 triggers caspase-8-dependent cleavage of gasdermin D and cell death.
Orning P, Weng D, Starheim K, Ratner D, Best Z, Lee B, Brooks A, Xia S, Wu H, Kelliher MA, Berger SB, Gough PJ, Bertin J, Proulx MM, Goguen JD, Kayagaki N, Fitzgerald KA, Lien E
Science. 2018 Nov 30;362(6418):1064-1069. doi: 10.1126/science.aau2818. Epub 2018 Oct 25. PubMed Article

Plasmids from Article

ID Plasmid Purpose
123365pDB-His-MBP-mGSDMDExpression of full-length mouse GSDMD in E. coli

Antibodies from Article