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Multiplexed Cre-dependent selection yields systemic AAVs for targeting distinct brain cell types.
Ravindra Kumar S, Miles TF, Chen X, Brown D, Dobreva T, Huang Q, Ding X, Luo Y, Einarsson PH, Greenbaum A, Jang MJ, Deverman BE, Gradinaru V
Nat Methods. 2020 May;17(5):541-550. doi: 10.1038/s41592-020-0799-7. Epub 2020 Apr 20.
PubMed Article

Plasmids from Article

ID Plasmid Purpose  
127847pUCmini-iCAP-PHP.V1non-standard AAV2 rep-AAV-PHP.V1 cap plasmid with AAV cap expression controlled by a tTA-TRE amplification system
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127848pUCmini-iCAP-PHP.V2non-standard AAV2 rep-AAV-PHP.V2 cap plasmid with AAV cap expression controlled by a tTA-TRE amplification system
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127849pUCmini-iCAP-PHP.B4non-standard AAV2 rep-AAV-PHP.B4 cap plasmid with AAV cap expression controlled by a tTA-TRE amplification system
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127851pUCmini-iCAP-PHP.Nnon-standard AAV2 rep-AAV-PHP.N cap plasmid with AAV cap expression controlled by a tTA-TRE amplification system
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Antibodies from Article