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PTPN21 and Hook3 relieve KIF1C autoinhibition and activate intracellular transport.

Siddiqui N, Zwetsloot AJ, Bachmann A, Roth D, Hussain H, Brandt J, Kaverina I, Straube A
Nat Commun. 2019 Jun 19;10(1):2693. doi: 10.1038/s41467-019-10644-9. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
130975pFastBac-M13-6His-KIF1C-GFP Expression of 6His-KIF1C-GFP in insect cells for protein purification.
130976pFastBacM13-8His-ZZ-LTLT-Hook3-SNAPf Expression of 8His-ZZ-LTLT tagged Hook3-SNAPf in insect cells for protein purification.
130980pKIF1C-BioID2-HAExpression of HA-tagged KIF1C-BioID2

Antibodies from Article