Skip to main content
This website uses cookies to ensure you get the best experience. By continuing to use this site, you agree to the use of cookies.

Please note: Your browser does not support the features used on Addgene's website. You may not be able to create an account or request plasmids through this website until you upgrade your browser. Learn more

Please note: Your browser does not fully support some of the features used on Addgene's website. If you run into any problems registering, depositing, or ordering please contact us at [email protected]. Learn more

Addgene
CRISPR-SONIC: targeted somatic oncogene knock-in enables rapid in vivo cancer modeling.
Mou H, Ozata DM, Smith JL, Sheel A, Kwan SY, Hough S, Kucukural A, Kennedy Z, Cao Y, Xue W
Genome Med. 2019 Apr 16;11(1):21. doi: 10.1186/s13073-019-0627-9.
PubMed Article

Plasmids from Article

ID Plasmid Purpose
138176H513 px330.sgActin.UTR.2CRISPR SONIC: Encodes codon-optimized SpCas9 and gRNA for targeting 3' UTR of β-actin.
138177H517 SONIC HRASV12 donorCRISPR SONIC: HRAS G12V donor plasmid
138178H516 SONIC KrasG12D-IRES-luciferase donorCRISPR SONIC: Kras G12D luciferase donor plasmid.

Antibodies from Article