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Non-V600 BRAF mutations recurrently found in lung cancer predict sensitivity to the combination of Trametinib and Dabrafenib.
Noeparast A, Teugels E, Giron P, Verschelden G, De Brakeleer S, Decoster L, De Greve J
Oncotarget. 2016 Aug 26;8(36):60094-60108. doi: 10.18632/oncotarget.11635. eCollection 2017 Sep 1.
PubMed Article

Plasmids from Article

ID Plasmid Purpose
131710p3xFLAG CMV14 / BRAFMammalian Expression of Flag tagged BRAF
131711p3xFLAG CMV14 / BRAF-G469AMammalian Expression of Flag tagged BRAF
131712p3xFLAG CMV14 / BRAF-G596CMammalian Expression of Flag tagged BRAF
131713p3xFLAG CMV14 / BRAF-D594NMammalian Expression of Flag tagged BRAF
131714p3xFLAG CMV14 / BRAF-D594EMammalian Expression of Flag tagged BRAF
131715p3xFLAG CMV14 / BRAF-D594VMammalian Expression of Flag tagged BRAF
131716p3xFLAG CMV14 / BRAF-G469SMammalian Expression of Flag tagged BRAF
131717p3xFLAG CMV14 / BRAF-D594AMammalian Expression of Flag tagged BRAF
131718p3xFLAG CMV14 / BRAF-G469VMammalian Expression of Flag tagged BRAF
131719p3xFLAG CMV14 / BRAF-D594GMammalian Expression of Flag tagged BRAF
131720p3xFLAG CMV14 / BRAF-V600KMammalian Expression of Flag tagged BRAF
131721p3xFLAG CMV14 / BRAF-V600RMammalian Expression of Flag tagged BRAF
131722p3xFLAG CMV14 / BRAF-G466VMammalian Expression of Flag tagged BRAF
131723p3xFLAG CMV14 / BRAF-V600EMammalian Expression of Flag tagged BRAF

Antibodies from Article