CRAF mutations in lung cancer can be oncogenic and predict sensitivity to combined type II RAF and MEK inhibition.
Noeparast A, Giron P, Noor A, Bahadur Shahi R, De Brakeleer S, Eggermont C, Vandenplas H, Boeckx B, Lambrechts D, De Greve J, Teugels E
Oncogene. 2019 Aug;38(31):5933-5941. doi: 10.1038/s41388-019-0866-7. Epub 2019 Jul 8. PubMed Article
Noeparast A, Giron P, Noor A, Bahadur Shahi R, De Brakeleer S, Eggermont C, Vandenplas H, Boeckx B, Lambrechts D, De Greve J, Teugels E
Oncogene. 2019 Aug;38(31):5933-5941. doi: 10.1038/s41388-019-0866-7. Epub 2019 Jul 8. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 131724 | pLenti-puro /BRAF-V600E | Mammalian Expression of Flag tagged BRAF |
| 131725 | pLenti-puro/RAF1 | Mammalian Expression of RAF1 |
| 131726 | pLenti-puro/RAF1-P207S | Mammalian Expression of RAF1 |
| 131727 | pLenti-puro/RAF1-S259A | Mammalian Expression of RAF1 |
| 131728 | pLenti-puro/RAF1-P261A | Mammalian Expression of RAF1 |