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The Integrator complex cleaves nascent mRNAs to attenuate transcription.
Tatomer DC, Elrod ND, Liang D, Xiao MS, Jiang JZ, Jonathan M, Huang KL, Wagner EJ, Cherry S, Wilusz JE
Genes Dev. 2019 Sep 17. pii: gad.330167.119. doi: 10.1101/gad.330167.119.
PubMed Article

Plasmids from Article

ID Plasmid Purpose
132643Hy_pMtnA eGFP MALAT1Expresses an eGFP mRNA from the Drosophila Metallothionein A promoter that ends in the MALAT1 triple helix
132644Hy_pPepck1 eGFP SV40Expresses eGFP mRNA from the Drosophila Pepck1 promoter
132645Hy_pHml eGFP SV40Expresses eGFP mRNA from the Drosophila Hml promoter
132646Hy_pCG8620 eGFP SV40Expresses eGFP mRNA from the Drosophila CG8620 promoter
132647Hy_pSirup eGFP SV40Expresses eGFP mRNA from the Drosophila Sirup promoter
132648Hy_ppst eGFP SV40Expresses eGFP mRNA from the Drosophila pst promoter
132649Hy_pCG6770 eGFP SV40Expresses eGFP mRNA from the Drosophila CG6770 promoter
132650Hy_pUbi-p63e eGFP SV40Expresses eGFP mRNA from the Drosophila Ubi-p63e promoter
132651Hy_pMtnA UTR 1-55 eGFP SV40Expresses an eGFP mRNA from the Drosophila Metallothionein A promoter that has 55 nt of the MtnA 5' UTR
132652Hy_pMtnA UTR delta 41-55 eGFP SV40Expresses an eGFP mRNA from the Drosophila Metallothionein A promoter that has 40 nt of the MtnA 5' UTR
132653Hy_pMtnA UTR delta 21-55 eGFP SV40Expresses an eGFP mRNA from the Drosophila Metallothionein A promoter that has 20 nt of the MtnA 5' UTR
132654Hy_pMtnA nLuc SV40Expresses nanoLuciferase (nLuc) mRNA from the Drosophila Metallothionein A promoter

Antibodies from Article