Master transcription factor reprograming unleashes selective translation promoting castration resistance and immune evasion in lethal prostate cancer.
Santasusagna S, Zhu S, Jawalagatti V, Carceles-Cordon M, Ertel A, Garcia-Longarte S, Song WM, Fujiwara N, Li P, Mendizabal I, Petrylak DP, Kelly WK, Reddy EP, Wang L, Schiewer MJ, Lujambio A, Karnes J, Knudsen KE, Cordon-Cardo C, Dong H, Huang H, Carracedo A, Hoshida Y, Rodriguez-Bravo V, Domingo-Domenech J
Cancer Discov. 2023 Sep 7. doi: 10.1158/2159-8290.CD-23-0306. PubMed Article
Santasusagna S, Zhu S, Jawalagatti V, Carceles-Cordon M, Ertel A, Garcia-Longarte S, Song WM, Fujiwara N, Li P, Mendizabal I, Petrylak DP, Kelly WK, Reddy EP, Wang L, Schiewer MJ, Lujambio A, Karnes J, Knudsen KE, Cordon-Cardo C, Dong H, Huang H, Carracedo A, Hoshida Y, Rodriguez-Bravo V, Domingo-Domenech J
Cancer Discov. 2023 Sep 7. doi: 10.1158/2159-8290.CD-23-0306. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 133308 | pGL4-eIF3B | Expression of luciferase driven by eIF3B promoter region |
| 133309 | pGL4-eIF3B MBE2 mutant | Expression of luciferase driven by eIF3B promoter region mutated at the E-box binding motif 2 |
| 133310 | pGL4-eIF3B MBE3 mutant | Expression of luciferase driven by eIF3B promoter region mutated at the E-box binding motif 3 |