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Enhanced CRISPR-based DNA demethylation by Casilio-ME-mediated RNA-guided coupling of methylcytosine oxidation and DNA repair pathways.
Taghbalout A, Du M, Jillette N, Rosikiewicz W, Rath A, Heinen CD, Li S, Cheng AW
Nat Commun. 2019 Sep 20;10(1):4296. doi: 10.1038/s41467-019-12339-7.
PubMed Article

Plasmids from Article

ID Plasmid  
134632pAT243_pX-sgRNA-5xPBSa-5xPBSc
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134643pAT888_CMV/CAG_PUFa-hTET1(CD)
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134649pAT890_CMV/CAG_dCas9-hTET1(CD)
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134650pAT801_CMV/CAG_TALE_A-hTET1(CD)
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134740pAT812_CMV/CAG_TALE_B-hTET1(CD)
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134830pAT817_CMV/CAG_TALE_F-hTET1(CD)
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134831pAT341_CMV/CAG_PUFa-TET1CD (H1671Y D1673A) (dead TET1)
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134835pAT360_CMV/CAG_PUFa-hGADD45A-hTET1(CD)
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134837pAT635_CMV/CAG_hGADD45A-PUFa-hTET1(CD)
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134838pAT355_CMV/CAG_PUFc-hGADD45A
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134846pAT356-CMV/CAG_hGADD45A-PUFc
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134848pAT892_CMV/CAG_PUFa-p65HSF1
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134849pAT608_CMV/CAG_Flag-hNEIL2-PUFa-hTET1(CD)
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134850pAT611_CMV/CAG_PUFa-hNEIL2-hTET1(CD)
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134851pAT595_CMV/CAG_PUFc-hNEIL2
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134855pAT596_CMV/CAG_hNEIL2-PUFc
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134856pAT699-CMV/CAG_Flag-hGADD45A-PUFa-hTET1(CD)
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134870pAT976_CMV/CAG_Flag-hGADD45A-PUFa-dTET1CD
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134871pAT971_CMV/CAG_Flag-hGADD45A (G39A)-PUFa-hTET1(CD)
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134872pAT972_CMV/CAG_Flag-hGADD45A (L77E)-PUFa-hTET1(CD)
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134873pAT973_CMV/CAG_FlaghGADD45A (G39A, L77E)-PUFa-hTET1(CD)
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134875pAT977_CMV/CAG_Flag-hNEIL2-PUFa-dTET1(CD)
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134876pAT1059_CMV/CAG_Flag-hNEIL2 (C291S)-PUFa-hTET1(CD)
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134877pAT1060_CMV/CAG_Flag-hNEIL2 (R310Q)-PUFa-hTET1(CD)
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134895pAT1089_PB-EF1a-Blast_2A_rtTA3-SV40pA_pCW-dCas9
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134975pAT1501-[PB-4xHSab-EF1a-Hygro_2A_rtTA3-SV40pA(-)_pCW-DEST]
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134976pAT1502-[PB-4xHSab-EF1a-Blast_2A_rtTA3-SV40pA(-)_pCW-DEST]
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134977pAT1090_PB-EF1a-Hygro_2A_rtTA3-SV40pA_pCW-Flag-PUFa-hTET1(CD)
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134978pAT1503_pX-SPFE-BbsI(ccdbCam)-5xPBSa
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134979pAT1504_pX-SPFE-BbsI(ccdbCam)-5xPBSc
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