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The DEAD-box protein DDX43 (HAGE) is a dual RNA-DNA helicase and has a K-homology domain required for full nucleic acid unwinding activity.
Talwar T, Vidhyasagar V, Qing J, Guo M, Kariem A, Lu Y, Singh RS, Lukong KE, Wu Y
J Biol Chem. 2017 Jun 23;292(25):10429-10443. doi: 10.1074/jbc.M117.774950. Epub 2017 May 3. PubMed Article

Plasmids from Article

ID Plasmid Purpose
134574pET28a-DDX43Express human DDX43 protein (WT, full-length) in E. coli
134575pET28a-DDX43-K292AExpress human DDX43 mutant (K292A, ATPase dead) in E. coli
134577pET28a-DDX43-FL-G84DExpress human DDX43 mutant (full-length with G84D mutation) in E. coli
134588pET28a-DDX43-NT-G46DExpress human DDX43 N-terminal region (1-253 aa, with G46D mutation) in E. coli

Antibodies from Article