Pyrin dephosphorylation is sufficient to trigger inflammasome activation in familial Mediterranean fever patients.
Magnotti F, Lefeuvre L, Benezech S, Malsot T, Waeckel L, Martin A, Kerever S, Chirita D, Desjonqueres M, Duquesne A, Gerfaud-Valentin M, Laurent A, Seve P, Popoff MR, Walzer T, Belot A, Jamilloux Y, Henry T
EMBO Mol Med. 2019 Oct 7:e10547. doi: 10.15252/emmm.201910547. PubMed Article
Magnotti F, Lefeuvre L, Benezech S, Malsot T, Waeckel L, Martin A, Kerever S, Chirita D, Desjonqueres M, Duquesne A, Gerfaud-Valentin M, Laurent A, Seve P, Popoff MR, Walzer T, Belot A, Jamilloux Y, Henry T
EMBO Mol Med. 2019 Oct 7:e10547. doi: 10.15252/emmm.201910547. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 134702 | p21-WT-MEFV | Lentiviral expression of human MEFV after doxycycline administration |
| 134703 | p21-M694V-MEFV | Lentiviral expression of human MEFV M694V after doxycycline administration |
| 134706 | p21-S208C/S242R/M694V-MEFV | Lentiviral expression of human MEFV S208C/S242R/M694V after doxycycline administration |
| 134709 | p21-S208C/M694V-MEFV | Lentiviral expression of human MEFV S208C/M694V after doxycycline administration |
| 134710 | p21-M694I-MEFV | Lentiviral expression of human MEFV M694I after doxycycline administration |
| 134711 | p21-M680I-MEFV | Lentiviral expression of human MEFV M680I after doxycycline administration |
| 134712 | p21-P369S-MEFV | Lentiviral expression of human MEFV P369S after doxycycline administration |