Optogenetic regulation of endogenous proteins.
Redchuk TA, Karasev MM, Verkhusha PV, Donnelly SK, Hulsemann M, Virtanen J, Moore HM, Vartiainen MK, Hodgson L, Verkhusha VV
Nat Commun. 2020 Jan 30;11(1):605. doi: 10.1038/s41467-020-14460-4.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 138973 | pQP-2460 | Light-induced recruitment of QPAS1-mCherry to the target protein bound to membrane; interaction occurs via intrabody fused to BphP1 |
| 138974 | pQP-2376 | Light-induced recruitment of NSImb-QPAS1-mCherry to the target protein bound to membrane; interaction occurs via intrabody fused to BphP1 |
| 138975 | pQP-2363 | Relocalization of genomically expressed protein of interest from cytoplasm to nucleus upon near-infrared illumination |
| 138976 | pQP-2473 | Nucleus-to-cytoplasm relocalization of genomically expressed GFP-fusion using NIR light controlled intrabody. |
| 138977 | pQP-NiRISB | Light-controlled tri-directional targeting of endogenous proteins (nucleus-shifted) |
| 138978 | pQP-CiRISB | Light-controlled tri-directional targeting of endogenous proteins (cytoplasm-shifted) |
| 138979 | pQP-iRISB | Light-controlled tri-directional targeting of endogenous proteins |
| 138980 | pQP-AR10 | Endogenous RAS regulation using light-controlled intrabody |