HELZ directly interacts with CCR4-NOT and causes decay of bound mRNAs.
Hanet A, Rasch F, Weber R, Ruscica V, Fauser M, Raisch T, Kuzuoglu-Ozturk D, Chang CT, Bhandari D, Igreja C, Wohlbold L
Life Sci Alliance. 2019 Sep 30;2(5). pii: 2/5/e201900405. doi: 10.26508/lsa.201900405. Print 2019 Oct. PubMed Article
Hanet A, Rasch F, Weber R, Ruscica V, Fauser M, Raisch T, Kuzuoglu-Ozturk D, Chang CT, Bhandari D, Igreja C, Wohlbold L
Life Sci Alliance. 2019 Sep 30;2(5). pii: 2/5/e201900405. doi: 10.26508/lsa.201900405. Print 2019 Oct. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 148474 | pSUPERpuro-BglII-HsHelz_AC | Mammalian Expression of HsHelz-shRNA |
| 148795 | pLIB-2STREP-HsHelz_1051-1942-GSSG-MBP_AG | Mammalian Expression of HsHelz_1051-1942-GSSG |
| 148796 | pLIB-2STREP-HsHelz-GSSG-MBP_AG | Mammalian Expression of HsHelz |
| 148797 | pLNHA-C1-HsHelz_AG | Mammalian Expression of HsHelz |
| 148798 | pnEA-NvM-HsHelz_1051-1474-GB1His6_AG | Bacterial Expression of HsHelz_1051-1474 |
| 148799 | pT7-EGFP-C1-HsHelz_AG | Mammalian Expression of HsHelz |
| 148800 | pT7-EGFP-C1-HsHelz-E795Q_AG | Mammalian Expression of HsHelz-E795Q |
| 148801 | pT7-EGFP-C1-HsHelz-E795QF1107V_AG | Mammalian Expression of HsHelz-E795QF1107V |
| 148802 | pT7-EGFP-C1-HsHelz-F1107V_AG | Mammalian Expression of HsHelz-F1107V |
| 148803 | pT7-EGFP-HsHelz_1-1050_AG | Mammalian Expression of HsHelz_1-1050 |
| 148804 | pT7-EGFP-HsHelz_1051-1942_AG | Mammalian Expression of HsHelz_1051-1942 |
| 148805 | pT7-MS2-HA-HsHelz_AG | Mammalian Expression of HsHelz |
| 148806 | pT7-MS2-HA-HsHelz_1-1050_AG | Mammalian Expression of HsHelz_1-1050 |
| 148807 | pT7-MS2-HA-HsHelz_1051-1942_AG | Mammalian Expression of HsHelz_1051-1942 |
| 148808 | pT7-MS2-HA-HsHelz-E795Q_AG | Mammalian Expression of HsHelz-E795Q |
| 148809 | pT7-MS2-HA-HsHelz-E795QF1107V_AG | Mammalian Expression of HsHelz-E795QF1107V |
| 148810 | pT7-MS2-HA-HsHelz-F1107V_AG | Mammalian Expression of HsHelz-F1107V |
| 148880 | pT7-MS2-HA-HsHelz_1-1474_AH | Mammalian Expression of HsHelz_1-1474 |
| 148881 | pAc5.1B-EGFP-DmHelz_AH | Insect Expression of DmHelz |
| 148882 | pAc5.1B-EGFP-DmHelz_1-1212_AH | Insect Expression of DmHelz_1-1212 |
| 148883 | pAc5.1B-EGFP-DmHelz_1213-2103_AH | Insect Expression of DmHelz_1213-2103 |
| 148884 | pAc5.1B-EGFP-DmHelz-E958Q_AH | Insect Expression of DmHelz-E958Q |
| 148885 | pAc5.1B-lambdaN-HA-DmHelz_AH | Insect Expression of DmHelz |
| 148886 | pAc5.1B-lambdaN-HA-DmHelz_1-1212_AH | Insect Expression of DmHelz_1-1212 |
| 148887 | pAc5.1B-lambdaN-HA-DmHelz_1213-2103_AH | Insect Expression of DmHelz_1213-2103 |
| 148888 | pAc5.1B-lambdaN-HA-DmHelz-E958Q_AH | Insect Expression of DmHelzE958Q |
| 148889 | pnEA-NvM-HsHelz_1475-1642del1595-1609-GB1His6_AH | Bacterial Expression of HsHelz_1475-1642-del1595-1609 |
| 148890 | pnEA-NvM-HsHelz_1475-1642-GB1His6_AH | Bacterial Expression of HsHelz_1475-1642 |
| 148891 | pnEA-NvM-HsHelz_1475-1942-GB1His6_AH | Bacterial Expression of HsHelz_1475-1942 |
| 148892 | pnEA-NvM-HsHelz_1643-1792del1746-1764-GB1His6_AH | Bacterial Expression of HsHelz_1643-1792-del1746-1764 |
| 148893 | pnEA-NvM-HsHelz_1643-1792-GB1His6_AH | Bacterial Expression of HsHelz_1643-1792 |
| 148894 | pnEA-NvM-HsHelz_1793-1914-GB1His6_AH | Bacterial Expression of HsHelz_1793-1914 |
| 148895 | pnEA-NvM-HsHelz_1793-1942del1890-1907-GB1His6_AH | Bacterial Expression of HsHelz_1793-1942-del1890-1907 |
| 148896 | pnEA-NvM-HsHELZ_1793-1942-GB1His6_AH | Bacterial Expression of HsHelz_1793-1942 |
| 148897 | pSpCas9-(BB)-2A-Puro-HsHelz-sgRNA_AH | Mammalian Expression of HsHelz-sgRNA |
| 148898 | pT7-EGFP-HsHelz_1-1474_AH | Mammalian Expression of HsHelz_1-1474 |
| 148899 | pT7-EGFP-HsHelz_1475-1942_AH | Mammalian Expression of HsHelz_1475-1942 |
| 148900 | pT7-MS2-HA-HsHelz_1475-1942_AH | Mammalian Expression of HsHelz_1475-1942 |