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A feed-forward loop between SorLA and HER3 determines heregulin response and neratinib resistance.
Al-Akhrass H, Conway JRW, Poulsen ASA, Paatero I, Kaivola J, Padzik A, Andersen OM, Ivaska J
Oncogene. 2021 Feb;40(7):1300-1317. doi: 10.1038/s41388-020-01604-5. Epub 2021 Jan 8.
PubMed Article

Plasmids from Article

ID Plasmid Purpose  
154892pDEST-SorLA-v1Expresses SorLA fused to Venus fragment 1 (v1) for use in bimolecular fluorescence complementation (BiFC) assays
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154893pDEST-ERBB3-v1Expresses ERBB3 (a.k.a HER3) fused to Venus fragment 1 (v1) for use in bimolecular fluorescence complementation (BiFC) assays
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154894pDEST-ERBB3-v2Expresses ERBB3 (a.k.a HER3) fused to Venus fragment 2 (v2) for use in bimolecular fluorescence complementation (BiFC) assays
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154895pDEST-ERBB2-v2Expresses ERBB2 (a.k.a HER2) fused to Venus fragment 2 (v2) for use in bimolecular fluorescence complementation (BiFC) assays
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154898pENTR2b-mVenusmVenus entry vector
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154899pEF.DEST51-mVenusExpresses a fluorescent protein, mVenus
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154900pDEST-SorLA-v2Expresses SorLA fused to Venus fragment 2 (v2) for use in bimolecular fluorescence complementation (BiFC) assays
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154901pDEST-ERBB2-v1Expresses ERBB2 fused to Venus fragment 1 (v1) for use in bimolecular fluorescence complementation (BiFC) assays
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Recombinant Antibodies from Article