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Dual base editor catalyzes both cytosine and adenine base conversions in human cells.
Zhang X, Zhu B, Chen L, Xie L, Yu W, Wang Y, Li L, Yin S, Yang L, Hu H, Han H, Li Y, Wang L, Chen G, Ma X, Geng H, Huang W, Pang X, Yang Z, Wu Y, Siwko S, Kurita R, Nakamura Y, Yang L, Liu M, Li D
Nat Biotechnol. 2020 Jun 1. pii: 10.1038/s41587-020-0527-y. doi: 10.1038/s41587-020-0527-y.
PubMed Article

Plasmids from Article

ID Plasmid Purpose  
157947A&C-BEmaxMammalian expression of A&C-BEmax
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157948AID-BE4max-P2A-GFPMammalian expression of AID-BE4max-P2A-GFP
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157949Lenti ABE7.10-N-AIDmaxLentiviral expression of ABE7.10-N-AIDmax
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157950Lenti AID-BEmaxLentiviral expression of AID-BEmax
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157951Lenti U6-HBG site1-EF1alpha-UGI-P2A-GFPLentiviral expression of HBG site 1 sgRNA
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Antibodies from Article