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Inhibitors of Coronavirus 3CL Proteases Protect Cells from Protease-Mediated Cytotoxicity.
Resnick SJ, Iketani S, Hong SJ, Zask A, Liu H, Kim S, Melore S, Lin FY, Nair MS, Huang Y, Lee S, Tay NES, Rovis T, Yang HW, Xing L, Stockwell BR, Ho DD, Chavez A
J Virol. 2021 Jun 24;95(14):e0237420. doi: 10.1128/JVI.02374-20. Epub 2021 Jun 24.
PubMed Article

Plasmids from Article

ID Plasmid Purpose  
160278pLEX307-SARS-CoV-2-3CLAllows for constituitive mammalian expression of the SARS-CoV-2 3CL protease via transfection or lentivirus
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160279pLEX307-SARS-CoV-2-3CL-C145AAllows for constituitive mammalian expression of the SARS-CoV-2 3CL protease with C145A mutation via transfection or lentivirus
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160280pLEX307-SARS-CoV-3CLAllows for constituitive mammalian expression of the SARS-CoV 3CL protease via transfection or lentivirus
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160281pLEX307-SARS-CoV-3CL-C145AAllows for constituitive mammalian expression of the SARS-CoV 3CL protease with C145A mutation via transfection or lentivirus
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160283pLEX307-MERS-CoV-3CL-C148AAllows for constituitive mammalian expression of the MERS-CoV 3CL protease with C145A mutation via transfection or lentivirus
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160284pLEX307-Bat-CoV-HKU9-3CLAllows for constituitive mammalian expression of the Bat-CoV-HKU9 3CL protease via transfection or lentivirus
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160285pLEX307-Bat-CoV-HKU9-3CL-C144AAllows for constituitive mammalian expression of the Bat-CoV-HKU9 3CL protease with C145A mutation via transfection or lentivirus
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160286pLEX307-HCoV-NL63-3CLAllows for constituitive mammalian expression of the HCoV-NL63 3CL protease via transfection or lentivirus
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160287pLEX307-HCoV-NL63-3CL-C144AAllows for constituitive mammalian expression of the HCoV-NL63 3CL protease with C144A mutation via transfection or lentivirus
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160288pLEX307-IBV-3CLAllows for constituitive mammalian expression of the IBV 3CL protease via transfection or lentivirus
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160289pLEX307-IBV-3CL-C143AAllows for constituitive mammalian expression of the IBV 3CL protease with C143A mutation via transfection or lentivirus
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Antibodies from Article