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Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I.
Yamamoto K, Venida A, Yano J, Biancur DE, Kakiuchi M, Gupta S, Sohn ASW, Mukhopadhyay S, Lin EY, Parker SJ, Banh RS, Paulo JA, Wen KW, Debnath J, Kim GE, Mancias JD, Fearon DT, Perera RM, Kimmelman AC
Nature. 2020 May;581(7806):100-105. doi: 10.1038/s41586-020-2229-5. Epub 2020 Apr 22.
PubMed Article

Plasmids from Article

ID Plasmid Purpose
161733pSLIK_Hyg_mTurquoise2_Atg4BC74ADoxycycline-inducible expression of Atg4B(C74A) fused with mTurquoise2 to inhibit autophagy
161734pINDUCER20_mStrawberryDoxycycline-inducible expression of mStrawberry
161735pINDUCER20_mStrawberry_Atg4BC74ADoxycycline-inducible expression of Atg4B(C74A) fused with mStrawberry to inhibit autophagy
161736pBabe_Zeo_cOVA_T2A_mStrawberryExpression of cOVA and mStrawberry
161737pBabe_Hyg_cOVA_T2A_mStrawberryExpression of cOVA and mStrawberry

Antibodies from Article