The glutathione peroxidase 8 (GPX8)/IL-6/STAT3 axis is essential in maintaining an aggressive breast cancer phenotype.
Khatib A, Solaimuthu B, Ben Yosef M, Abu Rmaileh A, Tanna M, Oren G, Schlesinger Frisch M, Axelrod JH, Lichtenstein M, Shaul YD
Proc Natl Acad Sci U S A. 2020 Sep 1;117(35):21420-21431. doi: 10.1073/pnas.2010275117. Epub 2020 Aug 18. PubMed Article
Khatib A, Solaimuthu B, Ben Yosef M, Abu Rmaileh A, Tanna M, Oren G, Schlesinger Frisch M, Axelrod JH, Lichtenstein M, Shaul YD
Proc Natl Acad Sci U S A. 2020 Sep 1;117(35):21420-21431. doi: 10.1073/pnas.2010275117. Epub 2020 Aug 18. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 161517 | GPX8 rescue PLAK1 | Rescues the expression of GPX8 in GPX8 plenti-CRISPR KO cells |
| 161518 | IL6R PLAK1 | Expresses IL6 receptor (full length) in mammalian cells. |
| 161519 | sIL6R PLAK1 | Expresses soluble IL6 receptor in mammalian cells. |