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Soluble CX3CL1 gene therapy improves cone survival and function in mouse models of retinitis pigmentosa.
Wang SK, Xue Y, Rana P, Hong CM, Cepko CL
Proc Natl Acad Sci U S A. 2019 May 14;116(20):10140-10149. doi: 10.1073/pnas.1901787116. Epub 2019 Apr 29.
PubMed Article

Plasmids from Article

ID Plasmid Purpose  
164421AAV-hRedOpsin-fCX3CL1AAV plasmid expressing full-length CX3CL1 (fractalkine) in photoreceptors
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164422AAV-Best1-sCX3CL1AAV plasmid expressing soluble CX3CL1 (fractalkine) in retinal pigment epithelium
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164424AAV-Best1-sCD200AAV plasmid expressing soluble CD200 in retinal pigment epithelium
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164425AAV-hRedOpsin-fCD200AAV plasmid expressing full-length CD200 in photoreceptors
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164426AAV-hRedOpsin-mCherryAAV plasmid expressing mCherry in photoreceptors
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Antibodies from Article