Programmable C-to-U RNA editing using the human APOBEC3A deaminase.
Huang X, Lv J, Li Y, Mao S, Li Z, Jing Z, Sun Y, Zhang X, Shen S, Wang X, Di M, Ge J, Huang X, Zuo E, Chi T
EMBO J. 2020 Nov 16;39(22):e104741. doi: 10.15252/embj.2020104741. Epub 2020 Oct 15. PubMed Article
Huang X, Lv J, Li Y, Mao S, Li Z, Jing Z, Sun Y, Zhang X, Shen S, Wang X, Di M, Ge J, Huang X, Zuo E, Chi T
EMBO J. 2020 Nov 16;39(22):e104741. doi: 10.15252/embj.2020104741. Epub 2020 Oct 15. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 164872 | TC1681 | CURE-C2: C to U RNA Editing, with high efficiency and high off-target effects |
| 164873 | TC1614 | CURE-X: C to U RNA Editing, with low off-target effects but also lower efficiency |
| 164874 | TC1332 | CURE-N: C to U RNA Editing, with high efficiency and low off-target effects |
| 164875 | TC1541A | Split GFP reporter expressing GFP(beta1-10) following C>U editing of the target site |
| 164876 | TC1154 | Split GFP reporter plasmid expressing GFP (b11beta |