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Development of siRNA payloads to target KRAS-mutant cancer.
Yuan TL, Fellmann C, Lee CS, Ritchie CD, Thapar V, Lee LC, Hsu DJ, Grace D, Carver JO, Zuber J, Luo J, McCormick F, Lowe SW
Cancer Discov. 2014 Oct;4(10):1182-1197. doi: 10.1158/2159-8290.CD-13-0900. Epub 2014 Aug 6. PubMed Article

Plasmids from Article

ID Plasmid Purpose
164926pInducer10b-HA-KRAS WT CO SRExpresses HA tagged, codon Optimized and siRNA-resistant, tetracycline-inducible KRAS wild type sequence
164928pInducer10b-HA-KRAS G12V CO SRExpresses HA tagged, codon Optimized and siRNA-resistant, tetracycline-inducible KRASG12V sequence

Antibodies from Article