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HDAC6 mediates an aggresome-like mechanism for NLRP3 and pyrin inflammasome activation.
Magupalli VG, Negro R, Tian Y, Hauenstein AV, Di Caprio G, Skillern W, Deng Q, Orning P, Alam HB, Maliga Z, Sharif H, Hu JJ, Evavold CL, Kagan JC, Schmidt FI, Fitzgerald KA, Kirchhausen T, Li Y, Wu H
Science. 2020 Sep 18;369(6510). pii: 369/6510/eaas8995. doi: 10.1126/science.aas8995.
PubMed Article

Plasmids from Article

ID Plasmid Purpose
166783pLV-mTurquoise2-IL-1beta-mNeonGreenFRET analysis (pro-IL-1beta cleavage) in living cells
166784pLV-mTurquoise2-Caspase-1-mNeonGreenFRET analysis (pro caspase-1 cleavage) in living cells

Antibodies from Article