HDAC6 mediates an aggresome-like mechanism for NLRP3 and pyrin inflammasome activation.
Magupalli VG, Negro R, Tian Y, Hauenstein AV, Di Caprio G, Skillern W, Deng Q, Orning P, Alam HB, Maliga Z, Sharif H, Hu JJ, Evavold CL, Kagan JC, Schmidt FI, Fitzgerald KA, Kirchhausen T, Li Y, Wu H
Science. 2020 Sep 18;369(6510). pii: 369/6510/eaas8995. doi: 10.1126/science.aas8995. PubMed Article
Magupalli VG, Negro R, Tian Y, Hauenstein AV, Di Caprio G, Skillern W, Deng Q, Orning P, Alam HB, Maliga Z, Sharif H, Hu JJ, Evavold CL, Kagan JC, Schmidt FI, Fitzgerald KA, Kirchhausen T, Li Y, Wu H
Science. 2020 Sep 18;369(6510). pii: 369/6510/eaas8995. doi: 10.1126/science.aas8995. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 166783 | pLV-mTurquoise2-IL-1beta-mNeonGreen | FRET analysis (pro-IL-1beta cleavage) in living cells |
| 166784 | pLV-mTurquoise2-Caspase-1-mNeonGreen | FRET analysis (pro caspase-1 cleavage) in living cells |