PLK1 facilitates chromosome biorientation by suppressing centromere disintegration driven by BLM-mediated unwinding and spindle pulling.
Addis Jones O, Tiwari A, Olukoga T, Herbert A, Chan KL
Nat Commun. 2019 Jun 28;10(1):2861. doi: 10.1038/s41467-019-10938-y. PubMed Article
Addis Jones O, Tiwari A, Olukoga T, Herbert A, Chan KL
Nat Commun. 2019 Jun 28;10(1):2861. doi: 10.1038/s41467-019-10938-y. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 110300 | pSpCas9(BB)-2A-Neo_h53BP1_gRNA_D | Expresssion of Cas9-T2A-neomycin resistant gene and a gRNA targeting exon 10 of human 53BP1 |