Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of nsp15 endoribonuclease.
Canal B, Fujisawa R, McClure AW, Deegan TD, Wu M, Ulferts R, Weissmann F, Drury LS, Bertolin AP, Zeng J, Beale R, Howell M, Labib K, Diffley JFX
Biochem J. 2021 Jul 16;478(13):2465-2479. doi: 10.1042/BCJ20210199. PubMed Article
Canal B, Fujisawa R, McClure AW, Deegan TD, Wu M, Ulferts R, Weissmann F, Drury LS, Bertolin AP, Zeng J, Beale R, Howell M, Labib K, Diffley JFX
Biochem J. 2021 Jul 16;478(13):2465-2479. doi: 10.1042/BCJ20210199. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 169166 | pBIG1a_3xFlag-6His-nsp15 (SARS-CoV-2) | Baculoviral transfer vector for the expression of SARS-CoV-2 nsp15 in insect cells |