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Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of nsp13 helicase.
Zeng J, Weissmann F, Bertolin AP, Posse V, Canal B, Ulferts R, Wu M, Harvey R, Hussain S, Milligan JC, Roustan C, Borg A, McCoy L, Drury LS, Kjaer S, McCauley J, Howell M, Beale R, Diffley JFX
Biochem J. 2021 Jul 16;478(13):2405-2423. doi: 10.1042/BCJ20210201.
PubMed Article

Plasmids from Article

ID Plasmid Purpose
169189pLIB_3xFlag-His6-nsp13 (SARS-CoV-2)Baculoviral transfer vector to express 3xFlag-His6-nsp13 (SARS-CoV-2) in insect cells
169190pLIB_GST-nsp13 (SARS-CoV-2)Baculoviral transfer vector to express GST-nsp13 (SARS-CoV-2) in insect cells

Antibodies from Article