Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of nsp13 helicase.
Zeng J, Weissmann F, Bertolin AP, Posse V, Canal B, Ulferts R, Wu M, Harvey R, Hussain S, Milligan JC, Roustan C, Borg A, McCoy L, Drury LS, Kjaer S, McCauley J, Howell M, Beale R, Diffley JFX
Biochem J. 2021 Jul 16;478(13):2405-2423. doi: 10.1042/BCJ20210201. PubMed Article
Zeng J, Weissmann F, Bertolin AP, Posse V, Canal B, Ulferts R, Wu M, Harvey R, Hussain S, Milligan JC, Roustan C, Borg A, McCoy L, Drury LS, Kjaer S, McCauley J, Howell M, Beale R, Diffley JFX
Biochem J. 2021 Jul 16;478(13):2405-2423. doi: 10.1042/BCJ20210201. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose | |
|---|---|---|---|
| 169189 | pLIB_3xFlag-His6-nsp13 (SARS-CoV-2) | Baculoviral transfer vector to express 3xFlag-His6-nsp13 (SARS-CoV-2) in insect cells |
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| 169190 | pLIB_GST-nsp13 (SARS-CoV-2) | Baculoviral transfer vector to express GST-nsp13 (SARS-CoV-2) in insect cells |
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