Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of Nsp14 RNA cap methyltransferase.
Basu S, Mak T, Ulferts R, Wu M, Deegan T, Fujisawa R, Tan KW, Lim CT, Basier C, Canal B, Curran JF, Drury LS, McClure AW, Roberts EL, Weissmann F, Zeisner TU, Beale R, Cowling VH, Howell M, Labib K, Diffley JFX
Biochem J. 2021 Jul 16;478(13):2481-2497. doi: 10.1042/BCJ20210219. PubMed Article
Basu S, Mak T, Ulferts R, Wu M, Deegan T, Fujisawa R, Tan KW, Lim CT, Basier C, Canal B, Curran JF, Drury LS, McClure AW, Roberts EL, Weissmann F, Zeisner TU, Beale R, Cowling VH, Howell M, Labib K, Diffley JFX
Biochem J. 2021 Jul 16;478(13):2481-2497. doi: 10.1042/BCJ20210219. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 169191 | pK27Sumo_His-SUMO-nsp10-nsp16 fusion (SARS-CoV-2) | To express nsp10-nsp16 fusion protein in E. coli |