Small-molecule-induced polymerization triggers degradation of BCL6.
Slabicki M, Yoon H, Koeppel J, Nitsch L, Roy Burman SS, Di Genua C, Donovan KA, Sperling AS, Hunkeler M, Tsai JM, Sharma R, Guirguis A, Zou C, Chudasama P, Gasser JA, Miller PG, Scholl C, Frohling S, Nowak RP, Fischer ES, Ebert BL
Nature. 2020 Dec;588(7836):164-168. doi: 10.1038/s41586-020-2925-1. Epub 2020 Nov 18. PubMed Article
Slabicki M, Yoon H, Koeppel J, Nitsch L, Roy Burman SS, Di Genua C, Donovan KA, Sperling AS, Hunkeler M, Tsai JM, Sharma R, Guirguis A, Zou C, Chudasama P, Gasser JA, Miller PG, Scholl C, Frohling S, Nowak RP, Fischer ES, Ebert BL
Nature. 2020 Dec;588(7836):164-168. doi: 10.1038/s41586-020-2925-1. Epub 2020 Nov 18. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 169931 | BCL6-GFP in Artichoke | Overexpression of Full Length of BCL6-GFP fusion |
| 169932 | BCL6-GFP (1-275AA) in Cilantro | Overexpression of 1-275AA BCL6-GFP fusion |
| 169933 | BCL6-GFP R28A in Artichoke | Overexpression of BCL6-GFP R28A mutant fusion |
| 169935 | BCL6-GFP G55A in Artichoke | Overexpression of BCL6-GFP G55A mutant fusion |
| 169936 | BCL6-GFP Y58A in Artichoke | Overexpression of BCL6-GFP Y58A mutant fusion |