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Mammalian retrovirus-like protein PEG10 packages its own mRNA and can be pseudotyped for mRNA delivery.
Segel M, Lash B, Song J, Ladha A, Liu CC, Jin X, Mekhedov SL, Macrae RK, Koonin EV, Zhang F
Science. 2021 Aug 20;373(6557):882-889. doi: 10.1126/science.abg6155.
PubMed Article

Plasmids from Article

ID Plasmid Purpose  
174858pCMV-MmPeg10rc4Expresses recoded mouse Peg10 in mammalian cells
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174859pCMV-HsPeg10rc3Expresses recoded human Peg10 in mammalian cells
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174860pCMV-SynAExpresses mouse syncytin A in mammalian cells
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174861pCMV-SynBExpresses mouse syncytin B in mammalian cells
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174862pCMV-Mm.cargo(Cre)Expresses mouse Peg10 cargoRNA encoding Cre recombinase
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174863pCMV-Hs.cargo(Cre)Expresses human Peg10 cargoRNA encoding Cre recombinase
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174864pCMV-Hs.cargo(Cas9)Expresses human Peg10 cargoRNA encoding SpCas9
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174865pCMV-Mm.cargo(Cas9)Expresses mouse Peg10 cargoRNA encoding SpCas9
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