IFITM proteins promote SARS-CoV-2 infection and are targets for virus inhibition in vitro.
Prelli Bozzo C, Nchioua R, Volcic M, Koepke L, Kruger J, Schutz D, Heller S, Sturzel CM, Kmiec D, Conzelmann C, Muller J, Zech F, Braun E, Gross R, Wettstein L, Weil T, Weiss J, Diofano F, Rodriguez Alfonso AA, Wiese S, Sauter D, Munch J, Goffinet C, Catanese A, Schon M, Boeckers TM, Stenger S, Sato K, Just S, Kleger A, Sparrer KMJ, Kirchhoff F
Nat Commun. 2021 Jul 28;12(1):4584. PubMed Article
Prelli Bozzo C, Nchioua R, Volcic M, Koepke L, Kruger J, Schutz D, Heller S, Sturzel CM, Kmiec D, Conzelmann C, Muller J, Zech F, Braun E, Gross R, Wettstein L, Weil T, Weiss J, Diofano F, Rodriguez Alfonso AA, Wiese S, Sauter D, Munch J, Goffinet C, Catanese A, Schon M, Boeckers TM, Stenger S, Sato K, Just S, Kleger A, Sparrer KMJ, Kirchhoff F
Nat Commun. 2021 Jul 28;12(1):4584. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 179955 | pCG_IFITM1 | Expression vector for human IFITM1. |
| 179956 | pCG_IFITM2 | Expression vector for human IFITM2. |
| 179957 | pCG_IFITM3 | Expression vector for human IFITM3. |
| 179958 | pCG_IFITM1-IRES_eGFP | Expression vector for human IFITM1. Co-expresses GFP controlled by an IRES element. |
| 179959 | pCG_IFITM2-IRES_eGFP | Expression vector for human IFITM2. Co-expresses GFP controlled by an IRES element. |
| 179960 | pCG_IFITM3-IRES_BFP | Expression vector for human IFITM3. Co-expresses BFP controlled by an IRES element. |