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A RUNX-CBFbeta-driven enhancer directs the Irf8 dose-dependent lineage choice between DCs and monocytes.
Murakami K, Sasaki H, Nishiyama A, Kurotaki D, Kawase W, Ban T, Nakabayashi J, Kanzaki S, Sekita Y, Nakajima H, Ozato K, Kimura T, Tamura T
Nat Immunol. 2021 Mar;22(3):301-311. doi: 10.1038/s41590-021-00871-y. Epub 2021 Feb 18. PubMed Article

Plasmids from Article

ID Plasmid Purpose
83306CSII-U6-gRNA-CBh-3xFLAG-PA-dCas9-P2A-PuroLentivirus vector to express guideRNA and dCas9 with puro resistant gene

Antibodies from Article