Addgene: The Protein Tyrosine Phosphatase SHP-1 (PTPN6) but Not CD45 (PTPRC) Is Essential for the Ligand-Mediated Regulation of CD22 in BCR-Ligated B Cells.

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Takeshi Tsubata
Alborzian Deh Sheikh et al

The Protein Tyrosine Phosphatase SHP-1 (PTPN6) but Not CD45 (PTPRC) Is Essential for the Ligand-Mediated Regulation of CD22 in BCR-Ligated B Cells.
Alborzian Deh Sheikh A, Akatsu C, Abdu-Allah HHM, Suganuma Y, Imamura A, Ando H, Takematsu H, Ishida H, Tsubata T
J Immunol. 2021 Jun 1;206(11):2544-2551. doi: 10.4049/jimmunol.2100109. Epub 2021 May 14. PubMed Article

Plasmids from Article

ID	Plasmid	Purpose
183719	pMX-SHP1C/S-ires-mCD8	Expresses the myc-tagged SHP-1 C453S mutant (SHP-1C/S) (substrate-trapping mutant) and mouse CD8.
183720	pMX-SHP1C-ires-hCD8	Expresses the myc-tagged catalytic domains of wild-type SHP-1.

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