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A synergy between mechanosensitive calcium- and membrane-binding mediates tension-sensing by C2-like domains.
Shen Z, Belcheva KT, Jelcic M, Hui KL, Katikaneni A, Niethammer P
Proc Natl Acad Sci U S A. 2022 Jan 4;119(1). pii: 2112390119. doi: 10.1073/pnas.2112390119.
PubMed Article

Plasmids from Article

ID Plasmid Purpose
187001Phat2-dr-cPla2-C2-EGFP-6HProtein Expression
187088Phat2-hs-cPla2-C2-EGFP-GHProtein Expression
187104Phat2-dr-cPla2-C2-mCherry-6HProtein Expression
187113pGEX-6P-1-hs-ALPS 1-ALPS2-EGFPProtein Expression
187114pGEX-6P-1-hs-ALPS 1-ALPS2-mCherryProtein Expression
187115Phat2-hs-PKCgamma-C2-EGFP-6HProtein Expression
187157Phat2-hs-AKT1-PH-EGFP-6HProtein Expression
187183Phat2-dr-cPla2-C2-L32A-L33A-EGFP-6HProtein Expression
187184Phat2-dr-cPla2-C2-L32F-L33F-EGFP-6HProtein Expression
187185Phat2-dr-cPla2-C2-Y90A-V91A-EGFP-6HProtein Expression
187186Phat2-dr-cPla2-C2-Y90F-V91F-EGFP-6HProtein Expression
187187Phat2-dr-cPla2-C2-D34K-D87K-EGFP-6HProtein Expression
187188Phat2-dr-cPla2-C2-D34R-D87R-EGFP-6HProtein Expression
187189Phat2-dr-Alox5-PLAT-EGFP-6HProtein Expression
187190Phat2-dr-Alox12-PLAT-EGFP-6HProtein Expression

Antibodies from Article