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Prokaryotic innate immunity through pattern recognition of conserved viral proteins.
Gao LA, Wilkinson ME, Strecker J, Makarova KS, Macrae RK, Koonin EV, Zhang F
Science. 2022 Aug 12;377(6607):eabm4096. doi: 10.1126/science.abm4096. Epub 2022 Aug 12. PubMed Article

Plasmids from Article

ID Plasmid Purpose
188786SeAvs1Avs1 from Salmonella enterica NCTC10718
188787EcAvs1Avs1 from Escherichia coli NCTC9036
188788EpAvs1Avs1 from Erwinia piriflorinigrans CFBP5888
188789EcAvs2Avs2 from Escherichia coli NCTC9087
188790Ec2Avs2Avs2 from Escherichia coli NCTC10650
188791SeAvs3Avs3 from Salmonella enterica NCTC13175
188792KvAvs3Avs3 from Klebsiella variicola PF-1
188793AcAvs3Avs3 from Arcobacter cryaerophilus M830A
188794EcAvs4Avs4 from Escherichia coli NCTC11132
188795Ec2Avs4Avs4 from Escherichia coli 382_h
188796KpAvs4Avs4 from Klebsiella pneumoniae UNMC_8078
188797CcAvs4Avs4 from Corallococcus coralloides DSM2259
188798Ec3Avs4Avs4 from Escherichia coli NCTC11132
188799SsAvs4Avs4 from Streptomyces sp. A244
188800Avs4_Archaeon_isolate_HyVt-335Avs4 from Archaeon isolate HyVt-335
188801Avs4_Sulfurospirillum_sp.Avs4 from Sulfurospirillum sp.
188802Avs4_ChimeraChimeric Avs4 with transmembrane effector
188803pCDF-SeAvs1Codon optimized SeAvs1 with C-terminal His tag
188804pCDF-EcAvs2Codon optimized EcAvs2 with C-terminal His tag
188805pCDF-SeAvs3Codon optimized SeAvs3 with C-terminal His tag
188806pCDF-EcAvs4Codon optimized EcAvs4 with C-terminal His tag
188807pCDF-KpAvs4Codon optimized KpAvs4 with C-terminal His tag
188808pCDF-CcAvs4Codon optimized CcAvs4 with C-terminal His tag
188809Portal_T3Portal protein from phage T3
188810Portal_T7Portal protein from phage T7
188811Portal_PhiV1Portal protein from phage PhiV1
188812Portal_PiscesPortal protein from phage Pisces
188813Portal_RsoP1EGYPortal protein from Ralstonia phage RsoP1EGY
188814Portal_uncultured_phagePortal protein from uncultured Caudovirales phage
188815Portal_prophage_Sphingopyxis_flavaPortal protein from Sphingopyxis flava R11H prophage
188816Portal_prophage_Desulfurococcales_archaeonPortal protein from Desulfurococcales archaeon ex4484_217_2 prophage
188817Portal_SP6Portal protein from phage SP6
188818Portal_ECBP5Portal protein from phage ECBP5
188819Portal_PGT2Portal protein from phage PGT2
188820Portal_MinornaPortal protein from phage Minorna
188821Portal_LidtsurPortal protein from phage Lidtsur
188822Portal_prophage_Escherichia_coli_1Portal protein from Escherichia coli NCTC9020 prophage
188823Portal_N4Portal protein from phage N4
188824Portal_ZL19Portal protein from phage ZL19
188825Portal_ST32Portal protein from phage ST32
188826Portal_prophage_Escherichia_coli_2Portal protein from Escherichia coli M885 prophage
188827Portal_P1Portal protein from phage P1
188828Portal_LambdaPortal protein from phage Lambda
188829Portal_P22Portal protein from phage P22
188830Portal_T5Portal protein from phage T5
188831Portal_CBA120Portal protein from phage CBA120
188832Portal_T4Portal protein from phage T4
188833Portal_HHV8Portal protein from human herpesvirus 8
188834Terminase_T3Large terminase from phage T3
188835Terminase_T7Large terminase from phage T7
188836Terminase_PhiV1Large terminase from phage PhiV1
188837Terminase_PiscesLarge terminase from phage Pisces
188838Terminase_RsoP1EGYLarge terminase from Ralstonia phage RsoP1EGY
188839Terminase_uncultured_phageLarge terminase from uncultured Caudovirales phage
188840Terminase_prophage_Sphingopyxis_flavaLarge terminase from Sphingopyxis flava R11H prophage
188841Terminase_prophage_Desulfurococcales_archaeonLarge terminase from Desulfurococcales archaeon ex4484_217_2 prophage
188842Terminase_SP6Large terminase from phage SP6
188843Terminase_ECBP5Large terminase from phage ECBP5
188844Terminase_PGT2Large terminase from phage PGT2
188845Terminase_MinornaLarge terminase from phage Minorna
188846Terminase_LidtsurLarge terminase from phage Lidtsur
188847Terminase_prophage_Escherichia_coli_1Large terminase from Escherichia coli NCTC9020 prophage
188848Terminase_N4Large terminase from phage N4
188849Terminase_ZL19Large terminase from phage ZL19
188850Terminase_ST32Large terminase from phage ST32
188851Terminase_prophage_Escherichia_coli_2Large terminase from Escherichia coli M885 prophage
188852Terminase_P1Large terminase from phage P1
188853Terminase_LambdaLarge terminase from phage Lambda
188854Terminase_P22Large terminase from phage P22
188855Terminase_T5Large terminase from phage T5
188856Terminase_CBA120Large terminase from phage CBA120
188857Terminase_T4Large terminase from phage T4
188858Terminase_HHV8Large terminase from human herpesvirus 8
188859Lidtsur-17Avs inhibitor Lidtsur-17
188860Forsur-6Avs inhibitor Forsur-6
188861Lidtsur-6Avs inhibitor Lidtsur-6

Antibodies from Article