A CRISPRi/a platform in human iPSC-derived microglia uncovers regulators of disease states.
Drager NM, Sattler SM, Huang CT, Teter OM, Leng K, Hashemi SH, Hong J, Aviles G, Clelland CD, Zhan L, Udeochu JC, Kodama L, Singleton AB, Nalls MA, Ichida J, Ward ME, Faghri F, Gan L, Kampmann M
Nat Neurosci. 2022 Aug 11. pii: 10.1038/s41593-022-01131-4. doi: 10.1038/s41593-022-01131-4. PubMed Article
Drager NM, Sattler SM, Huang CT, Teter OM, Leng K, Hashemi SH, Hong J, Aviles G, Clelland CD, Zhan L, Udeochu JC, Kodama L, Singleton AB, Nalls MA, Ichida J, Ward ME, Faghri F, Gan L, Kampmann M
Nat Neurosci. 2022 Aug 11. pii: 10.1038/s41593-022-01131-4. doi: 10.1038/s41593-022-01131-4. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 190719 | CYBL-SPI1-CEBPB-IRF5 | For microglia differentiation from iPSC |
| 190720 | AAVS1-MAFB-IRF8-CEBPA | For microglia differentiation from iPSC |