Monospecific and bispecific monoclonal SARS-CoV-2 neutralizing antibodies that maintain potency against B.1.617.
Peng L, Hu Y, Mankowski MC, Ren P, Chen RE, Wei J, Zhao M, Li T, Tripler T, Ye L, Chow RD, Fang Z, Wu C, Dong MB, Cook M, Wang G, Clark P, Nelson B, Klein D, Sutton R, Diamond MS, Wilen CB, Xiong Y, Chen S
Nat Commun. 2022 Mar 28;13(1):1638. doi: 10.1038/s41467-022-29288-3. PubMed Article
Peng L, Hu Y, Mankowski MC, Ren P, Chen RE, Wei J, Zhao M, Li T, Tripler T, Ye L, Chow RD, Fang Z, Wu C, Dong MB, Cook M, Wang G, Clark P, Nelson B, Klein D, Sutton R, Diamond MS, Wilen CB, Xiong Y, Chen S
Nat Commun. 2022 Mar 28;13(1):1638. doi: 10.1038/s41467-022-29288-3. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 192175 | HH02-LP Clone 2 heavy chain | Clone 2 heavy chain (HH02) |
| 192176 | HH06-LP Clone 6 heavy chain | Clone 6 heavy chain (HH06) |
| 192177 | HH13 Clone 13 heavy chain | Clone 13 heavy chain (HH013) |
| 192178 | HH13A Clone 13A heavy chain | Clone 13A heavy chain (HH13A) |
| 192179 | HK02-LP Clone 2 light chain | Clone 2 light chain (HK02) |
| 192182 | HK13A Clone 13A light chain | Clone 13A light chain (HK13A) |
| 192183 | Clone 16 - 1 HH02 pFUSE-IgG1-Hole mutation-hole-clone2 | Clone 16 (HH02) pFUSE-IgG1-Hole mutation-hole-clone2 |
| 192184 | Clone 16 - 2 HH06 pFUSE-IgG1-Knob-mutation knob-clone6 | Clone 16 (HH06) pFUSE-IgG1-Knob-mutation knob-clone6 |
| 192185 | Clone 16 - 3 HK02 pFUSE-IgG-human kappa VL-CH1 hole-clone2 | Clone 16 (HK02) pFUSE-IgG-human kappa VL-CH1 hole-clone2 |