A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.
Bergfort A, Preussner M, Kuropka B, Ilik IA, Hilal T, Weber G, Freund C, Aktas T, Heyd F, Wahl MC
Nat Commun. 2022 Mar 3;13(1):1132. doi: 10.1038/s41467-022-28754-2. PubMed Article
Bergfort A, Preussner M, Kuropka B, Ilik IA, Hilal T, Weber G, Freund C, Aktas T, Heyd F, Wahl MC
Nat Commun. 2022 Mar 3;13(1):1132. doi: 10.1038/s41467-022-28754-2. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 193367 | pETM30-C9ORF78 | Expression of C9ORF78 in E.coli with N-terminal His6-GST-tag which is cleavable with TEV protease |
| 193368 | pETM30-C9ORF78_R41A | Expression of C9ORF78 R41A variant in E.coli with N-terminal His6-GST-tag which is cleavable with TEV protease |
| 193369 | pETM30-C9ORF78_F8A | Expression of C9ORF78 F8A variant in E.coli with N-terminal His6-GST-tag which is cleavable with TEV protease |