Amplification of CRKL induces transformation and epidermal growth factor receptor inhibitor resistance in human non-small cell lung cancers.
Cheung HW, Du J, Boehm JS, He F, Weir BA, Wang X, Butaney M, Sequist LV, Luo B, Engelman JA, Root DE, Meyerson M, Golub TR, Janne PA, Hahn WC
Cancer Discov. 2011 Dec;1(7):608-25. doi: 10.1158/2159-8290.CD-11-0046. Epub 2011 Oct 17. PubMed Article
Cheung HW, Du J, Boehm JS, He F, Weir BA, Wang X, Butaney M, Sequist LV, Luo B, Engelman JA, Root DE, Meyerson M, Golub TR, Janne PA, Hahn WC
Cancer Discov. 2011 Dec;1(7):608-25. doi: 10.1158/2159-8290.CD-11-0046. Epub 2011 Oct 17. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 196015 | pLenti6.3_CRKL-silent-V5 | Expresses CRKL-silent, V5 tagged |
| 196016 | pLenti6.3_CRKL-Y207F-V5 | Expresses CRKL Y207F, V5 tagged |
| 196017 | pLenti6.3_CRKL-W160L-V5 | Expresses CRKL W160L, V5 tagged |
| 196018 | pLenti6.3_CRKL-WT-V5 | Expresses CRKL WT, V5 tagged |
| 196019 | pWzl_CRKL-W275L | Expresses CRKL W275L |
| 196020 | pWzl_CRKL-W160L+Y207F | Expresses Expresses CRKL W160L + Y207F |
| 196021 | pWzl_CRKL-W160L+W275L | Expresses CRKL W160L + W275L |
| 196022 | pWzl_CRKL-Y207F+W275L | Expresses CRKL Y207F + W275L |
| 196023 | plx304_CRKL-open-V5 | Expresses CRKL open, V5 tagged |