Structural insights into gammaH2Ax containing nucleosomes.

Panigrahi R, Edwards R, Islam MT, Lu J, Kulepa A, Kim TH, Mark Glover JN
Nucleic Acids Res. 2025 Oct 14;53(19):gkaf1028. doi: 10.1093/nar/gkaf1028. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID	Plasmid	Purpose
197272	His-huH3-huH4	Human (hu) histones H3 and H4 inserted into a plasmid
197273	His-huH2Ax(T137E_A139D_Q141E)-huH2B	Human (hu) histones H2Ax and H2B inserted into a plasmid. Contains the phosphomimetic substitutions T137E, A139D, and Q141E in H2Ax.
240442	HisH2A-InteinCBD-H2B	Expresses H2A-Intein-Chitinbinding domain bound to H2B