Integrated screens uncover a cell surface tumor suppressor gene KIRREL involved in Hippo pathway.
Wang C, Feng X, Su D, Chen Z, Wang S, Tang M, Huang M, Nie L, Zhang H, Li S, Yin L, Johnson RL, Hart T, Chen J
Proc Natl Acad Sci U S A. 2022 Jun 21;119(25):e2121779119. doi: 10.1073/pnas.2121779119. Epub 2022 Jun 15. PubMed Article
Wang C, Feng X, Su D, Chen Z, Wang S, Tang M, Huang M, Nie L, Zhang H, Li S, Yin L, Johnson RL, Hart T, Chen J
Proc Natl Acad Sci U S A. 2022 Jun 21;119(25):e2121779119. doi: 10.1073/pnas.2121779119. Epub 2022 Jun 15. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 200445 | Murine cell surface protein knockout (McspKO) library | A CRISPR library targeting 1,157 cell surface genes and 98 control genes with four sgRNAs per gene |