Light-activated macromolecular phase separation modulates transcription by reconfiguring chromatin interactions.
Kim YJ, Lee M Jr, Lee YT, Jing J, Sanders JT, Botten GA, He L, Lyu J, Zhang Y, Mettlen M, Ly P, Zhou Y, Xu J
Sci Adv. 2023 Mar 31;9(13):eadg1123. doi: 10.1126/sciadv.adg1123. Epub 2023 Mar 31. PubMed Article
Kim YJ, Lee M Jr, Lee YT, Jing J, Sanders JT, Botten GA, He L, Lyu J, Zhang Y, Mettlen M, Ly P, Zhou Y, Xu J
Sci Adv. 2023 Mar 31;9(13):eadg1123. doi: 10.1126/sciadv.adg1123. Epub 2023 Mar 31. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 200967 | dCas9-CRY2Clust-FUSN | induction of phase-separated condensate mediated by FUSN-IDR |
| 200968 | dCas9-CRY2Clust-BRD4ΔN | induction of phase-separated condensate mediated by BRD4dN-IDR |
| 200969 | dCas9-CRY2Clust | induction of phase-separated condensate by CRY2Clust |
| 200970 | dCas9-CRY2Clust-FUSN-mut | induction of phase-separated condensate mediated by FUSN-IDR mutant |