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Addgene
Frank von Delft Lab: The SARS-Cov-2 main protease (Mpro) is responsible for viral polyprotein processing and therefore a therapeutic target.
Unpublished

Plasmids from Article

ID Plasmid Purpose
204769Sars Cov 2 MPRO C145S mutantBacterial expression of Sars Cov 2 MPRO C145S mutant
204770Sars Cov 2 MPRO R188K mutantBacterial expression of Sars Cov 2 MPRO R188K mutant
204771Sars Cov 2 MPRO A193S mutantBacterial expression of Sars Cov 2 MPRO A193S mutant
204772Sars Cov 2 MPRO A191T mutantBacterial expression of Sars Cov 2 MPRO A191T mutant
204773Sars Cov 2 MPRO A193T mutantBacterial expression of Sars Cov 2 MPRO A193T mutant
204774Sars Cov 2 MPRO A191V mutantBacterial expression of Sars Cov 2 MPRO A191V mutant
204776Sars Cov 2 MPRO G143S mutantBacterial expression of Sars Cov 2 MPRO G143S mutant
204777Sars Cov 2 MPRO M49I mutantBacterial expression of Sars Cov 2 MPRO M49I mutant
204778Sars Cov 2 MPRO M165I mutantBacterial expression of Sars Cov 2 MPRO M165I mutant
204779Sars Cov 2 MPRO M49T mutantBacterial expression of Sars Cov 2 MPRO M49T mutant
204782Sars Cov 2 MPRO N142S mutantBacterial expression of Sars Cov 2 MPRO N142S mutant
204783Sars Cov 2 MPRO P132H mutantBacterial expression of Sars Cov 2 MPRO P132H mutant
204784Sars Cov 2 MPRO Q189K mutantBacterial expression of Sars Cov 2 MPRO Q189K mutant
204785Sars Cov 2 MPRO R188S mutantBacterial expression of Sars Cov 2 MPRO R188S mutant
204786Sars Cov 2 MPRO T190I mutantBacterial expression of Sars Cov 2 MPRO T190I mutant
204787Sars Cov 2 Mac domainBacterial expression of Sars Cov 2 Mac domain
204788Zika NS5 RdRpBacterial expression of Zika NS5 RdRp
204790MERS Mpro - His6-SUMO with autoprocessing - MSAVMQ/SGLVKM---MGVVMQ/SGVRKVTYGTAHWLBacterial expression of MERS Mpro
204791Fusion of Zika NS2B-NS3 proteinsBacterial expression of a fusion of Zika NS2B-NS3 proteins
204792Fusion of Dengue2 NS2B-NS3 proteinsBacterial expression of a fusion of Dengue2 NS2B-NS3 proteins
204793Fusion of Dengue2 NS2B-NS3 proteinsBacterial expression of a fusion of Dengue2 NS2B-NS3 proteins
204796Fusion of West Nile NS2B-NS3 proteinsBacterial expression of a fusion of West Nile NS2B-NS3 proteins
204797Fusion of West Nile NS2B-NS3Bacterial expression of a fusion of West Nile NS2B-NS3 proteins
204798Fusion of West Nile NS2B-NS3Bacterial expression of a fusion of West Nile NS2B-NS3 proteins
204799Fusion of West Nile NS2B-NS3Bacterial expression of a fusion of West Nile NS2B-NS3 proteins
204800Fusion of Dengue2 NS2B-NS3Bacterial expression of a fusion of Dengue2 NS2B-NS3 proteins
204801Enterovirus D68 2A proteaseBacterial expresison of Enterovirus D68 2A protease
204803Enterovirus D68 2A proteaseBacterial expresison of Enterovirus D68 2A protease
204804Enterovirus D68 2A proteaseBacterial expresison of Enterovirus D68 2A protease
204805Enterovirus D68 2A proteaseBacterial expresison of Enterovirus D68 2A protease
204806Co-expression of West Nile NS2B and NS3Bacterial co-expression of West Nile NS2B and NS3 proteins
204808Co-expression of Dengue2 NS2B and NS3Bacterial co-expression of Dengue2 NS2B and NS3 proteins
204809Enterovirus A71 2A proteaseBacterial expresison of Enterovirus A71 2A protease
204810Enterovirus A71 2A proteaseBacterial expresison of Enterovirus A71 2A protease
204811Enterovirus A71 2A proteaseBacterial expresison of Enterovirus A71 2A protease
204812Enterovirus A71 2A proteaseBacterial expresison of Enterovirus A71 2A protease
204813Enterovirus A71 2A proteaseBacterial expresison of Enterovirus A71 2A protease
204814MERS Mpro - His6-SUMO with autoprocessing - MSAVLQ/SGLVKM---MGVVMQ/SGVRKVTYGTAHWLBacterial expression of MERS Mpro
204815Fusion of Zika NS2B-NS3 proteinsBacterial expression of a fusion of Zika NS2B-NS3 proteins
204816Enterovirus A71 3C proteaseBacterial expresison of Enterovirus A71 3C protease
204817Enterovirus D68 3C proteaseBacterial expresison of Enterovirus D68 3C protease

Antibodies from Article