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Targeting AAV vectors to the central nervous system by engineering capsid-receptor interactions that enable crossing of the blood-brain barrier.
Huang Q, Chen AT, Chan KY, Sorensen H, Barry AJ, Azari B, Zheng Q, Beddow T, Zhao B, Tobey IG, Moncada-Reid C, Eid FE, Walkey CJ, Ljungberg MC, Lagor WR, Heaney JD, Chan YA, Deverman BE
PLoS Biol. 2023 Jul 19;21(7):e3002112. doi: 10.1371/journal.pbio.3002112. eCollection 2023 Jul.
PubMed Article

Plasmids from Article

ID Plasmid Purpose
203532iCAP-BI-28-KanRRepCap for AAV production
203533iCAP-BI-48-KanRRepCap for AAV production
203534iCAP-BI-49-KanRRepCap for AAV production
203535iCAP-BI-62-KanRRepCap for AAV production
203536iCAP-BI-65-KanRRepCap for AAV production

Antibodies from Article