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Addgene
Strand-selective base editing of human mitochondrial DNA using mitoBEs.
Yi Z, Zhang X, Tang W, Yu Y, Wei X, Zhang X, Wei W
Nat Biotechnol. 2023 May 22. doi: 10.1038/s41587-023-01791-y. PubMed Article

Plasmids from Article

ID Plasmid Purpose
2092939ao-SOD2-3xHA-TALE(ND4-Left)-Nt.BspD6I(C)mitoBE expression vector, target mtND4 gene.
20929419ag-SOD2-3xHA-TALE(RNR2-Left)-MutHmitoBE expression vector, target mtRNR2 gene.
20929622l-COX8-3xFlag-TALE(RNR2-Right)-TadA(8e+V106W)mitoBE expression vector, target mtRNR2 gene.

Antibodies from Article