Skip to main content

A design approach for bitopic kinase inhibitors

Stevenson JW, Lou K, Reynolds JA, Outhwaite IR, Huang K, Sokirniy I, Peterson SYJ, Munir AZ, Wang CD, Inam H, Gebauer EL, Leyte-Vidal A, Grynyova A, Figueroa SM, Rees MG, Ronan MM, Salangsang F, Zeng Y, Steri V, Roth JA, Shah NP, Echeverria I, Šali A, Zhang Z, Moslehi JJ, Seeliger MA, Pritchard JR, Shokat KM
2026, in press.

Plasmids from Article

ID Plasmid Purpose
210433pUltra BCR-ABL E255VLentiviral expression of BCR-ABL E255V
210434pUltra BCR-ABL T315ILentiviral expression of BCR-ABL T315I
210436pUltra BCR-ABL E255V T315ILentiviral expression of BCR-ABL E255V T315I
210437pUltra BCR-ABL T315MLentiviral expression of BCR-ABL T315M
210438pUltra BCR-ABL E255V V468FLentiviral expression of BCR-ABL E255V V468F
210439pUltra BCR-ABL T315I V468FLentiviral expression of BCR-ABL T315I V468F
210440pUltra BCR-ABL E255V T315I V468FLentiviral expression of BCR-ABL E255V T315I V468F
210441pUltra BCR-ABL T315M V468FLentiviral expression of BCR-ABL T315M V468F

Antibodies from Article