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TEAD Inhibition Overcomes YAP1/TAZ-driven Primary and Acquired Resistance to KRASG12C Inhibitors.
Edwards AC, Stalnecker CA, Jean Morales A, Taylor KE, Klomp JE, Klomp JA, Waters AM, Sudhakar N, Hallin J, Tang TT, Olson P, Post L, Christensen JG, Cox AD, Der CJ
Cancer Res. 2023 Nov 7. doi: 10.1158/0008-5472.CAN-23-2994. PubMed Article

Plasmids from Article

ID Plasmid Purpose
213583pInducer-YAP1Doxycycline inducible expression of YAP1 wild type cDNA in mammalian cells
213584pInducer-YAP1-S127ADoxycycline inducible expression of YAP1-S127A cDNA in mammalian cells
213585pInducer-YAP1-S127A/S397ADoxycycline inducible expression of YAP1-S127A/S397A cDNA in mammalian cells
213586pInducer-YAP1-S127A/S397A/S94ADoxycycline inducible expression of YAP1-S127A/S397A/S94A cDNA in mammalian cells
213587pInducer-TAZDoxycycline inducible expression of TAZ wild type cDNA in mammalian cells
213588pInducer-TAZ-S89ADoxycycline inducible expression of TAZ-S89A cDNA in mammalian cells
213589pInducer-TAZ-S89A/S311ADoxycycline inducible expression of TAZ-S89A/S311A cDNA in mammalian cells
213590pInducer-TAZ-S89A/S311A/S51ADoxycycline inducible expression of TAZ-S89A/S311A/S51A cDNA in mammalian cells

Antibodies from Article