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Synthetic integrin antibodies discovered by yeast display reveal alphaV subunit pairing preferences with beta subunits.
Hao Y, Yan J, Fraser C, Jiang A, Anuganti M, Zhang R, Lloyd K, Jardine J, Coppola J, Meijers R, Li J, Springer TA
bioRxiv [Preprint]. 2024 Jan 27:2024.01.26.577394. doi: 10.1101/2024.01.26.577394. PubMed Article

Plasmids from Article

No plasmids are currently publicly available from Addgene for this article.

Antibodies from Article

ID Antibody Purpose
213654 Anti-Integrin alpha V beta 8 [IPI-ITGAV/ITGB8.8] Anti-Integrin αVβ8 (Human) chimeric recombinant antibody with fused human variable and rabbit constant domains; binds the particular alpha/beta chain pair, does not block function
213655 Anti-Integrin alpha V beta 6 [IPI-ITGAV/ITGB6.2] Anti-Integrin αVβ6 (Human) chimeric recombinant antibody with fused human variable and rabbit constant domains; binds the particular alpha/beta chain pair, does not block function
213656 Anti-Integrin alpha V beta 6 [IPI-ITGAV/ITGB6.3] Anti-Integrin αVβ6 (Human) chimeric recombinant antibody with fused human variable and rabbit constant domains; binds the particular alpha/beta chain pair, blocks ligand binding/function (RGD-mimetic)
213657 Anti-Integrin alpha V beta 6 [IPI-ITGAV/ITGB6.4] Anti-Integrin αVβ6 (Human) chimeric recombinant antibody with fused human variable and rabbit constant domains; binds the particular alpha/beta chain pair, blocks ligand binding/function (RGD-mimetic)
213658 Anti-Integrin alpha V beta 6 [IPI-ITGAV/ITGB6.12] Anti-Integrin αVβ6 (Human) chimeric recombinant antibody with fused human variable and rabbit constant domains; binds the particular alpha/beta chain pair, blocks ligand binding/function (RGD-mimetic)