Peter Cockerill Lab: Development of receptor and oncogene-responsive luciferase reporter vectors that are activated via kinase signalling to AP-1.
Danial J L Coleman, Luke Ames, Hurooul Aain, Joanna Gamble, Kinga Koscielniak, Zijin Zhang, Cherisse Lau, Abigail Joyce, and Peter N Cockerill.
Experimental Hematology, 2026
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Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 71258 | pAP1-3 | luciferase reporter with 3 copies of the stromelylisin gene AP-1 site in front of hGM-CSF -55 to +28 minimal promoter |
| 217413 | LEGO-GM55 | Luciferase expression vector with the minimal GM-CSF promoter |
| 217414 | LEGO-AP1x3-GM55 | Luciferase expression vector with 3 AP-1 sites and the minimal GM-CSF promoter. Alias: LEGO-GM55-AP-1x3 |
| 217415 | LEGO-AP1x6-GM55 | Luciferase expression vector with 6 AP-1 sites and the minimal GM-CSF promoter. Alias: LEGO-GM55-AP-1x6 |
| 217416 | LEGO-pDHS-AP1x6-GM55 | Luciferase expression vector with 6 AP-1 sites and the minimal GM-CSF promoter, and a chromatin priming element. Alias: LEGO-GM55-AP-1x6-pDHS(IL-3) |
| 217418 | LEGO-pDHS-AP1x6-DUSP5 | Luciferase expression vector with 6 AP-1 sites and the full length DUSP5 promoter, and a chromatin priming element. Alias: LEGO-DUSP5p-AP-1x6 |
| 217419 | LEGO-pDHS-ITDE-AP1x6-DUSP5 | Luciferase expression vector with an oncogene-inducible enhancer, 6 AP-1 sites, the full length DUSP5 promoter, and a chromatin priming element. Alias: LEGO-DUSP5p-AP-1x6-ITDe |