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Structure-guided design of a peripherally restricted chemogenetic system.

Kang HJ, Krumm BE, Tassou A, Geron M, DiBerto JF, Kapolka NJ, Gumpper RH, Sakamoto K, Dewran Kocak D, Olsen RHJ, Huang XP, Zhang S, Huang KL, Zaidi SA, Nguyen MT, Jo MJ, Katritch V, Fay JF, Scherrer G, Roth BL
Cell. 2024 Dec 26;187(26):7433-7449.e20. doi: 10.1016/j.cell.2024.11.001. Epub 2024 Dec 3. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
228902pAAV-CAG-DIO-HA-HCARD-P2A-mCitrineFor AAV packaging and Cre dependent expression of a peripherally restricted DREADD

Antibodies from Article