Precise, minimally evolved adenine base editors generated through mutation reversion analysis.

Evanoff M, Korpal S, Krill ZD, Cowan QT, Komor AC
Nat Biotechnol. 2026 Mar 18. doi: 10.1038/s41587-026-03045-z. PubMed Article

Plasmids from Article

ID	Plasmid	Purpose
238067	pME270	Expresses ME-ABE ABE7.10-HRHSK with SpCas9 (NG)
238068	pME464	Expressed ME-ABE ABE7.10-HRHSK with SpRYCas9
238103	pME463	Expressed ME-ABE ABE7.10-HK with SpRYCas9
238104	pME234	Expresses ME-ABE ABE7.10-HK with SpCas9 (NG