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Proteome-scale tagging and functional screening in mammalian cells by ORFtag.

Nemcko F, Himmelsbach M, Loubiere V, Yelagandula R, Pagani M, Fasching N, Brennecke J, Elling U, Stark A, Ameres SL
Nat Methods. 2024 Sep;21(9):1668-1673. doi: 10.1038/s41592-024-02339-x. Epub 2024 Jul 5. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
220981ORFtag_TetR-SD_Frame1ORFtag viral retroviral vector containing a constitutively active promoter and a TetR tag followed by a splice donor sequence in Frame1
220982ORFtag_TetR-SD_Frame2ORFtag viral retroviral vector containing a constitutively active promoter and a TetR tag followed by a splice donor sequence in Frame2
220983ORFtag_TetR-SD_Frame3ORFtag viral retroviral vector containing a constitutively active promoter and a TetR tag followed by a splice donor sequence in Frame3
220984ORFtag_LambdaN-SD_Frame1ORFtag viral retroviral vector containing a constitutively active promoter and a LambdaN tag followed by a splice donor sequence in Frame1
220985ORFtag_LambdaN-SD_Frame2ORFtag viral retroviral vector containing a constitutively active promoter and a LambdaN tag followed by a splice donor sequence in Frame2
220986ORFtag_LambdaN-SD_Frame3ORFtag viral retroviral vector containing a constitutively active promoter and a LambdaN tag followed by a splice donor sequence in Frame3

Antibodies from Article